منابع مشابه
Bypass specialists operate together
New experiments show that different combinations of translesion DNA polymerases act to bypass lesions in mammalian cells, depending on the type of DNA damage. Bypass of most lesions tested was dependent on REV3L (pol zeta) and at least one additional DNA polymerase. The data fit a model whereby DNA polymerases work sequentially to bypass adducts in DNA.
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Multiple coordinated visualizations enable users to rapidly explore complex information. However, users often need unforeseen combinations of coordinated visualizations. Snaptogether visualization (Snap) enables users to rapidly and dynamically construct coordinated}visualization interfaces, customized for their data, without programming. Users load data into desired visualizations, then constr...
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BACKGROUND The importance of patient and public involvement (PPI) in healthcare decisions and research is increasingly recognised. This paper describes the aims, delivery, evaluation and impact of a 'Birdshot Day' organised for patients with birdshot uveitis, their carers and healthcare professionals. METHODS Delivery of this event involved the close collaboration of patients with a large num...
متن کاملHsp90α and Hsp90β together operate a hypoxia and nutrient paucity stress-response mechanism during wound healing.
When tissues are injured and blood vessels clot, the local environment becomes ischemic, meaning that there is a lack of adequate supply of oxygen and glucose delivered to the surrounding cells. The heat shock protein-90 (Hsp90) family proteins protect tissues from various environmental insults and participate in the repair of damaged tissue. Here, we report discovery of a new ischemia-responsi...
متن کاملWhen Specialists and Generalists Work Together: Overcoming Domain Dependence in Sentiment Tagging
This study presents a novel approach to the problem of system portability across different domains: a sentiment annotation system that integrates a corpus-based classifier trained on a small set of annotated in-domain data and a lexicon-based system trained on WordNet. The paper explores the challenges of system portability across domains and text genres (movie reviews, news, blogs, and product...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2009
ISSN: 0261-4189,1460-2075
DOI: 10.1038/emboj.2008.303